Tracking Down Mutations Cell by Cell

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Tracking Down Mutations Cell by Cell

Using somatic cell nuclear transfer, Hazen et al. (2016) examined clonally expanded single neurons for mutations and found ∼100 mutations from a variety of classes. Post-mitotic mutations in individual neurons represent an exploratory direction for finding fundamental origins of neurodegeneration.

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ژورنال

عنوان ژورنال: Neuron

سال: 2016

ISSN: 0896-6273

DOI: 10.1016/j.neuron.2016.02.042